A Consolidated Effort

" We never had enough space to realize our full potential. Now we'll have a new lab building where all three institutes can be together. "

Dr. Robert Mahley Gladstone President Emeritus

The J. David Gladstone Institutes is comprised of three distinct entities: the Institute of Cardiovascular Disease, the Institute of Virology and Immunology, and the Institute of Neurological Disease, and while completely independent, Gladstone is formally affiliated with the University of California, San Francisco (UCSF). After 25 years of being scattered across several buildings in San Francisco, the Gladstone leadership decided to consolidate its staff and move onto a new site at Mission Bay, adjacent to the UCSF campus.

The 195,000-square-foot building is designed to usher in a new sense of collaboration among the institutes’ growing research community. Each Gladstone institute has its own floor with approximately 100 workstations, or bench spaces, stretching in rows from one end of the building to the other. Offices and specialized lab space are arrayed in horizontal blocks, with lounge areas next to the bench spaces to encourage collaboration.Specialized laboratory spaces include a vivarium and BSL-3 suites

The interior layouts are designed to maximize the productivity of the research spaces by increasing the scientists’ interaction in four zones: laboratory, equipment support, office and shared core laboratory spaces. The laboratory, office and write-up areas are open and can be easily reconfigured to suit the changing needs of researchers. The equipment-intense support areas are more specific, but flexible due to their modular composition. Circulation intersections between these zones are marked by spatial nodes that promote casual discussion, white-board interfaces, conferencing and team-work areas.

Awards and Publications


San Francisco Business Times, Best New Office in San Francisco
Structural Engineers Association of Northern California, Excellence in Structural Engineering Award


San Francisco Chronicle, "Boost for biotech in SF: Gladstone Institutes to open Mission Bay research center,"
September 2004.